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Vitamin E has been shown to augment oxygen utilization during activity at peak [17], but does not attend to be an effective ergogenic unbefitting sea nuke conditions [18]. A contemporary review indicated that although vitamin E supplementation may increase tissue or serum vitamin E concentration, most evidence suggests there is no discernable effect on training, performance, or rate of post-exercise recovery in either recreational or elite athletes [19]. CoQ10, also known as ubiquinone, is an antioxidant and may improve oxygen uptake in the mitochondria of the heart, and has been used therapeutically for the treatment of cardiovascular disease. Theoretically, improved oxygen usage in the heart and skeletal muscles could improve aerobic endurance performance. Only limited data are available, but these studies have shown that CoQ10 supplementation to healthy young or older subjects did not influence lipid peroxidation, heart rate, maximal oxygen uptake, anaerobic threshold, or cycling endurance performance [20-23]. One study reported that CoQ10 supplementation was associated with muscle tissue damage and actually impaired cycling performance compared to the placebo treatment [24]. Overall, a recent review [25] concluded that there is limited evidence that dietary supplementation with antioxidants improves human performance.